Section 1: Basics of Infection
1. Defining Periprosthetic Joint Infections
2. Incidence and Burden of Periprosthetic Joint Infections
3. Economics of Periprosthetic Joint Infection
4. Antibiotics and Periprosthetic Joint Infection: Basic Science
5. The Role of Biofilm in Periprosthetic Joint Infection
6. Multidisciplinary Approach and Management of Patients with Periprosthetic Infections
7. Periprosthetic Joint Infection: Future Trends and Challenges

Section 2: Prevention
8. Predisposing Factors for Periprosthetic Joint Infection
9. Patient Medical Optimization
10. Preoperative Diabetic Maintenance and Control
11. Preoperative Skin Preparation: Decolonization and Antisepsis
12. Controversial Preventive Strategies
13. The Operating Room Environment
14. Incise Drapes
15. Antibiotic Prophylaxis
16. Workup of Patients with Suspected Urinary Tract Infection
17. Irrigation Solutions in Total Joint Arthroplasty
18. Bone Cement and Antibiotics
19. Blood Conservation
20. Wound Closure
21. Drains
22. Postarthroplasty Antibiotic Prophylaxis

Section 3: Diagnosis
23. AAOS Clinical Practice Guidelines: Diagnosis of Periprosthetic Joint Infections in Hip and Knee
24. Available Diagnostic Laboratory Tests
25. Aspiration
26. Molecular Markers in PJI
27. Imaging for Diagnosis of Periprosthetic Joint Infection
29. Culture-Negative Periprosthetic Joint Infection
30. Diagnosis of Prosthetic Joint Infection in Inflammatory Conditions
31. Conditions Mimicking Periprosthetic Joint Infection

Section 4: Treatment of PJI
32. Total Joint Arthroplasty in Patients with Prior Septic Arthritis
33. Joint Arthroplasty in Patients with Hardware In Situ
34. Management of Wound Drainage
35. Management of Fungal Periprosthetic Joint Infections
36. Management of Mycobacterial Infection
37. Management of Prosthetic Joint Infection Caused by Enterococcus
38. Irrigation and Debridement with Modular Component Exchange for Periprosthetic Joint Infection
39. One-Stage Exchange Arthroplasty for Periprosthetic Joint Infection
40. Resection Arthroplasty
41. Removal of Well-Fixed Hip and Knee Arthroplasty Components in the Setting of Periprosthetic Joint Infection
42. Two-Stage Exchange Arthroplasty: Antibiotic Spacers
43. Reimplantation Following Two-Stage Exchange Arthroplasty for Periprosthetic Joint Infection
44. Suppression of Prosthetic Joint Infection Using Antimicrobial Therapy
45. Prognostic Classification for Periprosthetic Joint Infection
46. Outcome in Periprosthetic Joint Infection Treatment
Index